January 29, 2013
At least 20% of all people, and almost half (46%) of all children
aged 5 to 19 years, were infected with H1N1 influenza during the first
year of the 2009 pandemic, according to a meta-analysis of data from 27
seroepidemiological studies. The studies analyzed approximately 90,000
serologic samples from 19 countries including the United States, United
Kingdom, Australia, Canada, China, and India.
Maria D. Van Kerhove, PhD, a liaison between the Global Influenza
Programme at the World Health Organization in Geneva, Switzerland, and
the Medical Research Council Centre for Outbreak Analysis and Modelling
at Imperial College London in the United Kingdom, and colleagues
published their findings in an article published online January 21 in Influenza and Other Respiratory Viruses.
Before the pandemic, the overall age-adjusted prevalence of elevated
cross-reactive H1N1pandemic (pdm) antibodies was 5% (95% confidence
interval [CI], 3% - 7%). The prevalence increased as individuals aged (0
- 4 years old, 1% [95% CI, 0.3% - 4%]; 5 - 19 years old, 4% [95% CI, 1%
- 9%]; 20 - 44 years old, 5% [95% CI, 3% - 8%]; and 45 - 64 years old,
5% [95% CI, 2% - 9%]). Prevalence was the highest in individuals at
least 65 years old (14%; 95% CI, 8% - 24%).
Continued: http://www.medscape.com/viewarticle/778445
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