Sunday, March 11, 2012

Pet dogs—A transmission route for human noroviruses?

Journal of Clinical Virology
Volume 53, Issue 3 , Pages 244-247, March 2012

Abstract
Background

Human noroviruses (HuNoVs) are one of the leading causes of diarrhoeal diseases worldwide in all age groups. Virus transmission can occur via the faecal-oral route from person to person or via contaminated food, water, or surfaces. The most common NoV strains circulating among humans belong to genogroup GII. Thus far, to our knowledge, no HuNoVs have been detected in pets.
Objectives

We investigated whether pet dogs could serve as carriers for HuNoVs and thereby transmit the infection to humans.
Study design

Ninety-two faecal samples of indoor pet dogs were obtained. The main criteria for sample collection were that the dog or humans in the household had suffered from diarrhoea or vomiting. All samples were screened for HuNoV genogroups GI, GII, and GIV by real-time one-step RT-PCR.
Results

We detected HuNoV in four faecal samples from pet dogs that had been in direct contact with symptomatic persons. Three of the positive samples contained genotype GII.4 variant 2006b or 2008 and one GII.12. All NoV-positive dogs lived in households with small children and two dogs showed mild symptoms.
Conclusions

Our results suggest that HuNoVs can survive in the canine gastrointestinal tract. Whether these viruses can replicate in dogs remains unresolved, but an association of pet dogs playing a role in transmission of NoVs that infect humans is obvious.


Also this podcast:

Dog runs and mooing miRs


Vincent, Alan, and Rich consider whether pet dogs might transmit human noroviruses, and an RNA virus microRNA that might be involved in oncogenesis.
http://www.twiv.tv/2012/03/11/twiv-174-dog-runs-and-mooing-mirs/

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